From PBPK to PBFTPK (physiologically-based finite time pharmacokinetic) models
A one day seminar by Athena RC on the occasion of the 30th Page Meeting
28-06-2022
Online
On the occasion of the 30th PAGE MEETING: Welcome to the Population Approach Group in Europe that will take place 28 June -1 July 2022, in Slovenia, Athena Research Center is organizing the online one-day seminar “From PBPK to PBFTPK (physiologically-based finite time pharmacokinetic) models” on 28 June, at 9.00 pm (CET).
This seminar is intended for Academics/students or scientists working in Academia, pharmaceutical industries, regulatory agencies, and contract research organizations.
It focuses on physiologically-based pharmacokinetic (PBPK) modeling and the recently developed physiologically-based finite time pharmacokinetic models. There is a great deal of interest on this topic across academia, industry and regulators, as reflected by a new draft guidance by FDA.
The full program of the seminar and information about the speakers and their presentations can be found here. To register at the seminar, please click here.
Scientific Program
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Time
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Speaker
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Topic
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08:55
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Panos Macheras
Department of Pharmacy, National & Kapodistrian Univeristy of Athens
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Welcome – Introduction
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09:00
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Panos Macheras
Department of Pharmacy, National & Kapodistrian Univeristy of Athens
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The false assumption that breaks pharmacokinetics of oral drug absorption.
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09:30
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Panos Macheras
Department of Pharmacy, National & Kapodistrian Univeristy of Athens
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The rise of physiologically based finite time pharmacokinetic (PBFTPK) models
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10:30
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Coffee Break
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11:00
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Pavlos Chrysafidis
Department of Pharmacy, National & Kapodistrian Univeristy of Athens
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Analysis of pharmacokinetic data using the PBFTPK software
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11.30
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Panos Macheras
Department of Pharmacy, National & Kapodistrian Univeristy of Athens
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Implications of finite absorption time on Bioavailability and Bioequivalence
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12.00
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Light lunch
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13.00
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Nikos ALimbertis
Department of Pharmacy, National & Kapodistrian Univeristy of Athens
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Analysis of bioequivalence data using the finite absorption time (FAT) concept
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13.30
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Rebeka Jereb
Sandoz development center, Ljubljana, Slovenia
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Evaluating the impact of gastrointestinal tract properties on drug in vivo performance using PBPK modeling and virtual clinical trials
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14.00
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Sandra Cvijic
Department of Pharmaceuitcal Technology, University of Belgrade
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Tackling the challenges of PBPK modeling for inhaled drugs
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14:30
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Coffee Break
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15:00
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Iztok Grabnar
Faculty of Pharmacy, University of Ljubljana
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Modeling complex absorption in a population analysis using empirical functions
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15:30
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Ioannis Loisios Konstantinidis
Novartis, Basel, Switzerland
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PBPK-IVIVE linked models to inform virtual bioequivalence trials
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16:00
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Filippos Kesisoglou
Merck & Co., Inc., Rahway, NJ, USA
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Can PBPK Modeling Streamline Food Effect Assessments?
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16:30
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Wrap-up & end of workshop
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Image credit VisitLjubljana.com