From PBPK to PBFTPK (physiologically-based finite time pharmacokinetic) models

A one day seminar by Athena RC on the occasion of the 30th Page Meeting

28-06-2022
Online

On the occasion of the 30th PAGE MEETING: Welcome to the Population Approach Group in Europe that will take place 28 June -1 July 2022, in Slovenia, Athena Research Center is organizing the online one-day seminar “From PBPK to PBFTPK (physiologically-based finite time pharmacokinetic) models” on 28 June, at 9.00 pm (CET).
 
This seminar is intended for Academics/students or scientists working in Academia, pharmaceutical industries, regulatory agencies, and contract research organizations.
 
It focuses on physiologically-based pharmacokinetic (PBPK) modeling and the recently developed physiologically-based finite time pharmacokinetic models.  There is a great deal of interest on this topic across academia, industry and regulators, as reflected by a new draft guidance by FDA.
 
The full program of the seminar and information about the speakers and their presentations can be found here. To register at the seminar, please click here.
 
Scientific Program
 
Time
Speaker
Topic
08:55
Panos Macheras
Department of Pharmacy, National & Kapodistrian Univeristy of Athens
Welcome – Introduction
09:00
Panos Macheras
Department of Pharmacy, National & Kapodistrian Univeristy of Athens
The false assumption that breaks pharmacokinetics of oral drug absorption.
09:30
Panos Macheras
Department of Pharmacy, National & Kapodistrian Univeristy of Athens
The rise of physiologically based finite time pharmacokinetic (PBFTPK) models
 
10:30
Coffee Break
11:00
Pavlos Chrysafidis
Department of Pharmacy, National & Kapodistrian Univeristy of Athens
Analysis of pharmacokinetic data using the PBFTPK software
11.30
 Panos Macheras
Department of Pharmacy, National & Kapodistrian Univeristy of Athens
Implications of finite absorption time on Bioavailability and Bioequivalence
 
12.00
Light lunch
13.00
Nikos ALimbertis
Department of Pharmacy, National & Kapodistrian Univeristy of Athens
Analysis of bioequivalence data using the finite absorption time (FAT) concept
13.30
 
Rebeka Jereb
Sandoz development center, Ljubljana, Slovenia
 
Evaluating the impact of gastrointestinal tract properties on drug in vivo performance using PBPK modeling and virtual clinical trials
 
 
14.00
Sandra Cvijic 
Department of Pharmaceuitcal Technology,  University of Belgrade
Tackling the challenges of PBPK modeling for inhaled drugs
14:30
 Coffee Break
 
15:00
Iztok Grabnar
Faculty of Pharmacy, University of Ljubljana
Modeling complex absorption in a population analysis using empirical functions
15:30
Ioannis Loisios Konstantinidis
Novartis, Basel, Switzerland
PBPK-IVIVE linked models to inform virtual bioequivalence trials
16:00
Filippos Kesisoglou
Merck & Co., Inc., Rahway, NJ, USA
Can PBPK Modeling Streamline Food Effect Assessments?
16:30
Wrap-up & end of workshop
 
 
 
Image credit VisitLjubljana.com
 
 
 
 
  

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