At an increasing rate, industrial and scientific institutions need to deal with massive data flows streaming in from a multitude of sources. For instance, maritime surveillance applications combine high-velocity data streams, including vessel position signals emitted from hundreds of thousands of vessels across the world and acoustic signals of autonomous, unmanned vessels; in the financial domain, stock price forecasting and portfolio management rely on stock tick data combined with real-time information sources on various pricing indicators; at the fight against cancer, complex simulations of multi-cellular systems are used, producing extreme-scale data streams in an effort to predict the effects of drug synergies on cancer cells. In these applications, the data volumes are expected to dramatically grow in the future. Processing this data often requires not only using an HPC infrastructure, but also having data scientists, who are typically not expert programmers, program complex workflows, with a vast number of parameters to tune through time-consuming repeated programming and testing. INFORE will address these challenges and pave the way for real-time, interactive extreme-scale analytics and forecasting. The ability to forecast, as early as possible, a good approximation to the outcome of a time-consuming and resource-demanding computational task allows to quickly identify undesired outcomes and save valuable amount of time, effort and computational resources, which would otherwise be spent in vain. Consider, for example, the ability to forecast the outcome of a complex multi-cellular system simulation for tumor evolution, without the need to wait for the simulation to be completed. INFORE will also design and develop a flexible, pluggable, distributed software architecture that is programmable and set up by graphical data processing workflows. The INFORE prototype will be tested on massive real-world data from the life sciences, financial and maritime domains.